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ItemCountPrice Order Compare
Butalbital APAP w/ caffeine 50 mg 30 $68.00 $0.045/mg
Butalbital APAP w/ caffeine 50 mg 60 $89.00 $0.030/mg
Butalbital APAP w/ caffeine 50 mg 90 $98.00 $0.024/mg
Fioricet 50 mg 30 $80.00 $0.053/mg
Fioricet 50 mg 60 $138.00 $0.046/mg
Fioricet 50 mg 90 $150.00 $0.033/mg
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Fioricet Facts

Contains 50mg butalbital, 325mg acetaminophen, 40mg caffeine
November, 2003 - Fioricet acquired by Watson Pharma (press release)
November, 1984 - Fioricet approved by FDA
Fioricet is designed for tension headache relief (not tested for migraines)
Fioricet is not scheduled by the DEA as a controlled substance

Fioricet: Clinical Results

The following paragraphs about Fioricet are by Teri Robert at About.com's Migraine/Headache Section. Medications containing butalbital, aspirin, acetaminophen, and/or caffeine [Fioricet] are used by many "headachers" for tension-type headache (TTH) and Migraine. They have been shown to be effective in placebo-controlled trials conducted with TTH patients, but have not been studied in placebo-controlled trials with Migraineurs.

The use of analgesics containing Butalbital [Fioricet] is controversial. Fioricet is banned in Germany, and expert advisory panels elsewhere have warned of their potential for abuse. Some experts warn that butalbital is likely to lead to rebound headache and/or dependence and question whether their benefit outweighs these problems. Teri Robert's comment: "Butalbital-containing analgesics [Fioricet] may be effective as backup medications or when other medications are ineffective or cannot be used. Because of concerns about overuse, medication-overuse headache, and withdrawal, Fioricet use should be limited and carefully monitored."

Fioricet Web.com summary Fioricet is effective for tension-type headaches, but there are no clinical trials for Fioricet relative to migraine headaches. User comments suggest that Fioricet can be helpful with migraines, but the results are mixed. Fioricet has its share of negative qualities. First is the rebound headaches, which many Fioricet users have reported. Second is the potential for addiction. Germany has taken measures to ban Fioricet and any drug containing butalbital. In contrast, Fioricet is legal in the United States and is not controlled by the DEA.

PDR Fioricet Highlights

PDR states the most important thing to know about Fioricet is "Mental and physical dependence can occur with the use of barbiturates such as Fioricet when taken in higher than recommended doses over long periods of time." PDR also notes: "Fioricet's active ingredient, Butalbital, slows the central nervous system (CNS) and intensifies the effects of alcohol and other CNS depressants. Use of alcohol with Fioricet may also cause overdose symptoms. Avoid alcoholic beverages while taking Fioricet."

Fioricet is effective for tension-type headaches, but there are no clinical trials for Fioricet relative to migraine headaches. User comments suggest that Fioricet can be helpful with migraines, but the results are mixed. Fioricet has its share of negative qualities.

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